Correlation of lumbar spine TBS with distal radius and tibial trabecular density and structure measured with HR-pQCT in men and women in the Toronto Cohort of the Canadian Multicentre Osteoporosis Study (CaMOS)

To better estimate the risk of bone fractures, both bone mineral density (BMD) and microarchitecture should be measured. Dual-energy X-ray absorptiometry(DXA) scans are clinically used to provide information about BMD and can be used to determine trabecular bone score (TBS), which gives an estimate of trabecular microarchitecture for lumbar spine(L1-L4). High-resolution pQCT (HRpQCT) is an in vivo measurement of bone microstructure of the distal radius and tibia and its images can be converted to finite elements for estimation of bone strength.
Source: Journal of Clinical Densitometry - Category: Radiology Authors: Source Type: research