The feasibility of ureteral tissue engineering using autologous veins: an orthotopic animal model with long term results

Conclusions: Venous grafts may be a potential source for ureteral reconstruction. The results of so far published ureteral tissue engineering projects reveal data up to 12 weeks after implantation. Even if the animal numbers of this study are small, there is an increasing rate of hydronephrosis revealing failure of ureteral tissue engineering with autologous matrices in time points longer than 3 months after implantation. Further investigations have to prove adequate clinical outcome and appropriate functional long-term results.
Source: Journal of Negative Results in BioMedicine - Category: Research Authors: Source Type: research