Allantoic metabolites, progesterone and estradiol-17 β remain unchanged after infection in an experimental model of equine ascending placentitis
The objective of this study was to characterize the metabolomic profile of equine allantoic fluid in the pregnant mare with and without experimentally induced ascending placentitis, with the goal of identifying biomarkers of this disease. We compared the onset of metabolomic changes to common modalities for diagnosis of ascending placentitis, including measurement of the combined thickness of the uterus and placenta (CTUP), hormonal profiling, and measurement of serum acute phase proteins. Ten pregnant pony mares were randomly divided into two groups: five healthy control mares (CONT), and five mares induced to develop ascending placentitis (PLAC) via inoculation with Streptococcus equi subsp.
Source: Journal of Equine Veterinary Science - Category: Veterinary Research Authors: Theresa Beachler, Hanna Gracz, Nathan M. Long, Luke Borst, David Morgan, Amber Nebel, Natalie Andrews, Joanna Koipillai, Samantha Frable, Stasia Bembenek-Bailey, Katelyn Ellis, Karen Von Dollen, Sara Lyle, John Gadsby, Christopher Scott Bailey Source Type: research