Pharmacogenetics of artemether ‐lumefantrine influence on nevirapine disposition: clinically significant drug‐drug interaction?

ConclusionsThis approach highlights additional increase in the already existing risk of suboptimal trough plasma concentration, especially in extensive metabolisers when nevirapine is co ‐administered with artemether‐lumefantrine.

Source: British Journal of Clinical Pharmacology - November 24, 2018 Category: Drugs & Pharmacology Authors: Sa ’ad T. Abdullahi, Adeniyi Olagunju, Julius O. Soyinka, Rahman A. Bolarinwa, Olusola J. Olarewaju, Moji T. Bakare‐Odunola, Andrew Owen, Saye Khoo Tags: ORIGINAL ARTICLE Source Type: research