In Vivo imaging characterization and anticancer efficacy of a novel HER2 Affibody and Pemetrexed conjugate in lung Cancer model

In this study, a new agent consisting of HER2-specific affibody ZHER2:V2 and chemotherapy drug pemetrexed was synthesized to develop a new targeted drug. Its biological characteristics and anticancer efficacy were assessed in cells level and xenografts models by radiolabeling with technetium-99  m.

Source: Nuclear Medicine and Biology - November 28, 2018 Category: Nuclear Medicine Authors: Honglei Jiao, Xinming Zhao, Jiahui Liu, Tuo Ma, Zhaoqi Zhang, Jingmian Zhang, Jianfang Wang Source Type: research