Fetal fraction ‐based risk algorithm for non‐invasive prenatal testing: screening for trisomies 13 and 18 and triploidy in women with low cell‐free fetal DNA
ConclusionsFor pregnancies with a FF too low to receive a result on standard NIPT, the FFBR algorithm identified a subset of cases at increased risk for trisomy 13, trisomy 18 or triploidy. For the remainder of cases, the risk of a fetal chromosomal abnormality was unchanged from that expected based on MA and GA. © 2018 The Authors.Ultrasound in Obstetrics& Gynecology published by John Wiley& Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.
Source: Ultrasound in Obstetrics and Gynecology - Category: Radiology Authors: T. McKanna,
A. Ryan,
S. Krinshpun,
S. Kareht,
K. Marchand,
C. Grabarits,
M. Ali,
A. McElheny,
K. Gardiner,
K. LeChien,
M. Hsu,
D. Saltzman,
M. Stosic,
K. Martin,
P. Benn Tags: Original Paper Source Type: research