Spatial and temporal coordination of antiviral responses by group 1 ILCs

SummaryGroup 1 innate lymphocytes consist of a phenotypically, spatially, and functionally heterogeneous population of NK cells and ILC1s that are engaged during pathogen invasion. We are only beginning to understand the context ‐dependent roles that different subsets of group 1 innate lymphocytes play during homeostatic perturbations. With a focus on viral infection, this review highlights the organization and regulation of spatially and temporally distinct waves of NK cell and ILC1 responses that collectively serve to a chieve optimal viral control.
Source: Immunological Reviews - Category: Allergy & Immunology Authors: Tags: INVITED REVIEW Source Type: research