Calcium-Ask1-MKK7-JNK2-c-Src Signaling Cascade Mediates Disruption of Intestinal Epithelial Tight Junctions by Dextran Sulfate Sodium

This study demonstrates that Ca2+-Ask1-MKK7-JNK2-cSrc signaling cascade mediates DSS-induced tight junction disruption and barrier dysfunction.

Source: BJ Cell - November 7, 2014 Category: Biochemistry Authors: G Samak, K K Chaudhry, R Gangwar, D Narayanan, J H Jaggar, R Krishna Rao Tags: BJ Signal Source Type: research