Improving Bone Mineral Density Assessment Using Spectral Detector CT

Introduction: Bone mineral density (BMD) analysis by Dual-Energy x-ray Absorptiometry (DXA) can have some false negatives due to overlapping structures in the projections. Spectral Detector CT (SDCT) can overcome these limitations by providing volumetric information. We investigated its performance for BMD assessment and compared it to DXA and phantomless volumetric bone mineral density (PLvBMD), the latter known to systematically underestimate BMD. DXA is the current standard for BMD assessment, while PLvBMD is an established alternative for opportunistic BMD analysis using CT.

Source: Journal of Clinical Densitometry - November 26, 2018 Category: Radiology Authors: Steven Van Hedent, Kuan-Hao Su, David W. Jordan, Brendan Eck, Fan Liang, Rivka Kessner, Jung-Wen Kuo, Nico Buls, Paul Klahr, Pablo Ros, Raymond F. Muzic Source Type: research