Optimization of arabinogalactan and taxifolin extraction process from Dahurian larch (Larix gmelinii) and evaluation of the effects on activities of α‐amylase, α‐glycosidase, and pancreatic lipase in vitro

In this study, response surface methodology of Plackett –Burman design and Box–Behnken design performed well to obtain the optimal conditions and satisfactory extraction yields for the extraction of arabinogalactan and taxifolin fromLarix gmelinii by ultrasonic microwave synergistic extraction method, which could be a good paradigm for the efficient isolation of bioactive substances from plant matrix in the field of separation science. Meanwhile, the results from the evaluation of the effects of two target compounds on activities of α‐amylase, α‐glycosidase, and pancreatic lipasein vitro revealed that larch arabinogalactan and taxifolin enjoyed the completely opposite influences on the three digestive enzymes, namely larch arabinogalactan could act as an inhibitor while taxifolin an accelerator. These results will facilitate the application of larch arabinogalactan and taxifolin in the food and pharmaceutical industries.

Source: Journal of Food Biochemistry - October 24, 2018 Category: Food Science Authors: Zaizhi Liu, Mengxia Wei, Guoqiang Cui, Xinyu Yang, Huiyan Gu, Lei Yang Tags: FULL ARTICLE Source Type: research