Comparative single ‐dose pharmacokinetics of orally administered florfenicol in rainbow trout (Oncorhynchus mykiss, Walbaum, 1792) at health and experimental infection with Streptococcus iniae or Lactococcus garvieae

In conclusion, infection with these bacteria can affect the pharmacokinetic behavior of florfenicol in rainbow trouts as shown by decreased bioavailability and increased total body clearance and volume of distribution inL.  garvieae infection and decreased volume of distribution accompanied by increasedCmax inS.  iniae‐infected fish.
Source: Journal of Veterinary Pharmacology and Therapeutics - Category: Veterinary Research Authors: Tags: ORIGINAL ARTICLE Source Type: research