Clinical and Biological Determinants of Sclerostin Plasma Concentration in Hemodialysis Patients

Conclusions: We confirm a higher concentration of sclerostin in HD patients, a positive association with age and a negative association with PTH. A positive association with phosphate, homocysteine and troponin calls for additional research. The clinical interest of sclerostin to assess vascular calcifications in HD is limited and no association was found between sclerostin and mortality.Nephron Clin Pract
Source: Nephron Clinical Practice - Category: Urology & Nephrology Source Type: research