Immobilized Cu(II) Schiff base complex supported on Fe3O4 magnetic nanoparticles: A highly efficient and reusable new catalyst for the synthesis of pyranopyridine derivatives

A novel copper(II) Schiff ‐base complex immobilized on silica‐coated nonmagnetic Fe3O4 was synthesized from acetylacetonate (acac) and 2 ‐aminothiophenol (ATP). The catalytic activity of Fe3O4@SiO2‐acac‐2ATP‐Cu(II) nanoparticles was explored in three‐component synthesis of pyrano[2,3‐b]pyridine derivative under solvent ‐free conditions. A new copper(II) Schiff base complex immobilized on silica ‐coated nanomagnetic Fe3O4 was synthesized from acetylacetonate (acac) and 2 ‐aminothiophenol (ATP). The newly synthesized nanocatalyst, Fe3O4@SiO2‐acac‐2ATP‐Cu(II), was structurally characterized using several analytical techniques. The catalytic activity of the Fe3O4@SiO2‐acac‐2ATP‐Cu(II) nanoparticles was investigated for the synthesis of pyrano[2,3‐b]pyridine derivatives from the one ‐pot three‐component reaction of aldehydes, malononitrile and 3‐cyano‐6‐hydroxy‐4‐methylpyridin‐2(1H) ‐one. A high catalytic performance was exhibited by this nanocatalyst under solvent‐free conditions and excellent yields of the products were achieved in reasonably short reaction times. The nanoparticles could be easily separated from the reaction mixture simply by magnetic decantation and reus ed for several consecutive runs without significant loss of catalytic activity.

Source: Applied Organometallic Chemistry - October 11, 2018 Category: Chemistry Authors: Davood Azarifar, Samaneh Mahmoudi ‐GomYek, Masoumeh Ghaemi Tags: FULL PAPER Source Type: research