CoFe2O4/TMU ‐17‐NH2 as a hybrid magnetic nanocomposite catalyst for multicomponent synthesis of dihydropyrimidines

A new magnetic metal ‐organic framework nanocomposite (CoFe2O4/TMU ‐17‐NH2) was prepared via embedding approach by synthesis of the MOF crystals in the presence of magnetic cobalt ferrite nanoparticles. A new magnetic metal –organic framework nanocomposite (CoFe2O4/TMU ‐17‐NH2) was prepared via an embedding approach by synthesis of the metal –organic framework crystals in the presence of magnetic cobalt ferrite nanoparticles. We demonstrated that the resulting magnetic nanocomposite can serve as a recyclable nanocatalyst for one‐pot synthesis of bis‐3,4‐dihydropyrimidin‐2(1H) ‐one and 3,4‐dihydropyrimidin‐2(1H) ‐one derivatives via three‐component reaction of 1,3‐diketone, urea or thiourea and aromatic aldehyde under solvent‐free conditions. CoFe2O4/TMU ‐17‐NH2 was characterized using various techniques. The recovery of the nanocomposite was achieved by a simple magnetic decantation and it was reused at least seven times without significant degradation in catalytic activity.

Source: Applied Organometallic Chemistry - October 31, 2018 Category: Chemistry Authors: Mahtab Yadollahi, Hosein Hamadi, Valiollah Nobakht Tags: FULL PAPER Source Type: research