Randomized trial: The effect of oral polio vaccine at birth on polio antibody titers at 6weeks and 6months of age

Conclusions OPV0 may contribute to early polio protection, particularly in children of mothers with low antibody levels. However, OPV0 did not contribute to overall polio immunity after subsequent doses of OPV were given, and was associated with significantly lower antibody titers in children of mothers with high antibody levels. However, it did not negatively affect the proportion of seropositive children.
Source: Trials in Vaccinology - Category: Infectious Diseases Source Type: research