The LepRdb/db mice model for studying glycation in the context of diabetes.

ConclusionsThedb/db model better reflected the characteristics of human T2D compared with the DIO models, and exhibited greater formation and accumulation of both furosine and protein ‐bound CML in all of the organs tested here.

Source: Diabetes/Metabolism Research and Reviews - November 22, 2018 Category: Endocrinology Authors: Axel Guilbaud, Michael Howsam, Celine Niquet ‐Léridon, Florian Delguste, Eric Boulanger, Frédéric J. Tessier Tags: RESEARCH ARTICLE Source Type: research