Capsule shell material impacts the in vitro disintegration and dissolution behaviour of a green tea extract

Conclusions The delayed release from studied HPMC capsule materials is likely attributed to an interaction between the catechins, the major constituents of the green tea extract, and the capsule shell material. An assessment of in vitro dissolution is recommended prior to the release of a dietary supplement or clinical trial investigational product to ensure efficacy. Graphical abstract
Source: Results in Pharma Sciences - Category: Drugs & Pharmacology Source Type: research