Proteomic analysis of dentin –enamel junction and adjacent protein‐containing enamel matrix layer of healthy human molar teeth

This study identified 46 proteins in DEJ and EOM. The protei ns identified have a variety of functions, including calcium ion‐binding, formation of extracellular matrix, formation of cytoskeleton, cytoskeletal protein binding, cell adhesion, and transport. Collagens were identified as the most dominant proteins. Tissue‐specific proteins, such as ameloblas tin and amelogenin, were also detected. Our findings reveal new insight into proteomics of DEJ and EOM, highly mineralized tissues that are obviously difficult to analyze.

Source: European Journal of Oral Sciences - November 22, 2018 Category: Dentistry Authors: Michal J ágr, Peter Ergang, Statis Pataridis, Marta Kolrosová, Martin Bartoš, Ivan Mikšík Tags: Original Article Source Type: research