Reduced Lateral Orbitofrontal Cortex (OFC) Volume and Suicide Behavior in Youth with Bipolar Disorder

ConclusionsThe OFC is involved in decision ‐making, impulsivity, and reward circuitry which have shown to be impaired in BD. Reduced OFC volume and its association with lethality of suicide suggest that suicide behavior in BD may be related to the emerging neuroanatomical substrates of the disorder, particularly abnormalities of the OFC.This article is protected by copyright. All rights reserved.

Source: Bipolar Disorders - November 24, 2018 Category: Psychiatry Authors: Rebekah S. Huber, Punitha Subramaniam, Douglas G. Kondo, Xianfeng Shi, Perry F. Renshaw, Deborah A. Yurgelun ‐Todd Tags: Original Article Source Type: research