Cancer stem cells as a therapeutic target in bladder cancer

In this study, we briefly discuss the biology of bladder cancer and then address the possible relationship between molecular biology of bladder cancer and  cancer stem cells. Subsequently, the mechanisms of resistance applied by cancer stem cells against the conventional therapeutic tools, especially chemotherapy, are discussed. Moreover, by emphasizing the biomarkers described for cancer stem cells in bladder cancer, we have provided, described, and proposed targets on cancer stem cells for therapeutic interventions and, finally, reviewed some immunotargeting strategies against bladder cancer stem cells.
Source: Journal of Cellular Physiology - Category: Cytology Authors: Tags: MINI REVIEW Source Type: research