Zyxin ‐involved actin regulation is essential in the maintenance of vinculin focal adhesion and chondrocyte differentiation status

ConclusionsThese results demonstrate supporting evidence that in chondrocytes the level of zyxin is closely associated with the state of actin polymerization. In particular, the change of zyxin and F ‐actin parallels with the change of COL II and vinculin, respectively, indicating a major role of zyxin‐actin interaction in the synthesis of collagen ECM and the remodelling of cytoskeleton‐ECM adhesion.

Source: Cell Proliferation - October 17, 2018 Category: Cytology Authors: Gaoming Li, Xiongbo Song, Rui Li, Li Sun, Xiaoyuan Gong, Cheng Chen, Liu Yang Tags: ORIGINAL ARTICLE Source Type: research