IL ‐33 guides osteogenesis and increases proliferation and pluripotency marker expression in dental stem cells

ConclusionsIL ‐33 treatment impairs osteogenesis of PDLSCs and DPSCs, while increases their clonogenicity, proliferation and pluripotency marker expression. After exposure to IL‐33, osteogenic capacity of cells stayed intact. NF‐κB and β‐catenin are implicated in the effects achieved by IL‐33 in PDLSC s and DPSCs.

Source: Cell Proliferation - November 14, 2018 Category: Cytology Authors: Tamara Kukolj, Drenka Trivanovi ć, Slavko Mojsilović, Ivana Okić Djordjević, Hristina Obradović, Jelena Krstić, Aleksandra Jauković, Diana Bugarski Tags: ORIGINAL ARTICLE Source Type: research