Sedative, analgesic, and behavioral effects of nalbuphine-xylazine and nalbuphine-midazolam combinations in dogs

The purpose of the present study was to evaluate the sedative, analgesic, and behavioral effects of nalbuphine-xylazine (NX) and nalbuphine-midazolam (NM) combinations for neuroleptanalgesia in dogs. A prospective randomized crossover study was done on six adult mongrel dogs. Dogs were randomly allocated into NX and NM groups with a washout period 2  weeks. Nalbuphine was given at dose of 0.5 mg/kg IV approximately 20 minutes before administration of the tranquilizer. Dogs were randomly allocated into one of the two groups: NX group received xylazine at a dose of 1 mg/kg IV; and NM group received midazolam at a dose of 0.5 mg/kg IV.
Source: Journal of Veterinary Behavior: Clinical Applications and Research - Category: Veterinary Research Authors: Tags: Canine Research Source Type: research