Toll-Like Receptor 2 and 4 expression in the Pregnant and Non-pregnant Human Uterine Cervix

Sexually transmitted infections (STIs) are a major worldwide health problem, compromising reproductive fecundity, causing morbidity, and reducing life expectancy (WHO, 2012; Adams et al., 2000). Maternal urogenital infections may lead to miscarriage, chorioamnionitis and congenital foetal infection and appear to be implicated in premature births (Lyon et al., 2010), the principal cause of perinatal mortality and handicap in surviving children (Christiaens et al., 2008).

Source: Journal of Reproductive Immunology - November 5, 2014 Category: Allergy & Immunology Authors: Behnia S. Lashkari, Shahida Shahana, Dilly O. Anumba Source Type: research