MUC5B, CA9 and CLDN18 are potential theranostic markers of gallbladder carcinoma

ConclusionsCLDN18 is a new metaplasia marker in gallbladder tissues and is conserved in roughly half of GBC cases. MUC5B and CA9 are highly conserved along GBC histological progression. The three markers are potential theranostic markers, in particular CA9 and CLDN18, for which there are already targeted therapies available.This article is protected by copyright. All rights reserved.

Source: Histopathology - November 22, 2018 Category: Pathology Authors: Jaime A. Espinoza, Ismael Riquelme, Eduardo A. Sagredo, Lorena Rosa, Patricia Garc ía, Carolina Bizama, María Apud‐Bell, Pamela Leal, Helga Weber, Felipe Benavente, Sergio Vargas, Diego Romero, Alexis M. Kalergis, Juan Carlos Roa Tags: Original Article Source Type: research