Diagnostic potential of sarcoplasmic myxovirus resistance protein A expression in subsets of dermatomyositis

ConclusionsSarcoplasmic MxA expression is more sensitive than PFA and RIG ‐I expression for a pathological diagnosis of DM, regardless of the autoantibody‐related subgroup. In light of its high sensitivity and specificity, it may be considered a pathological hallmark of DMper se. Also, lack of MxA expression in ASS supports the idea that ASS is a distinct entity from DM.

Source: Neuropathology and Applied Neurobiology - November 22, 2018 Category: Neurology Authors: A. Uruha, Y. Allenbach, J. ‐L. Charuel, L. Musset, A. Aussy, O. Boyer, K. Mariampillai, O. Landon‐Cardinal, C. Rasmussen, L. Bolko, T. Maisonobe, S. Leonard‐Louis, S. Suzuki, I. Nishino, W. Stenzel, O. Benveniste Tags: Original Article Source Type: research