Effects of a nutraceutical combination in patients with chronic lumbosacral radicular pain.

Effects of a nutraceutical combination in patients with chronic lumbosacral radicular pain. Funct Neurol. 2018 Jul/Sept;33(3):125-130 Authors: Geroin C, Tamburin S, Pagano G, Gandolfi M, Tinazzi M Abstract Drugs used for the treatment of chronic lumbosacral radicular pain (LRP) may have frequent adverse effects leading to medication withdrawal. The use of add-on nutraceuticals, which have no side effects, may therefore play a role in LRP treatment. We performed a six-week, single-center, open label prospective uncontrolled clinical study to evaluate the effect of a nutraceutical combination (Noxiall®) used as an add-on therapy in patients with chronic LRP. Fifteen patients were treated with Noxiall® twice a day for 10 consecutive days, followed by once-daily administration up to the end of the six-week treatment. The participants were evaluated at two visits (before-after), when primary and secondary outcomes were assessed. We found a significant reduction in pain severity post-treatment, as assessed using a numerical rating scale (p= 0.03), and a significant reduction in painkiller intake (p=0.03). Nutraceuticals could be a complementary therapy for chronic LRP. PMID: 30457964 [PubMed - in process]
Source: Functional Neurology - Category: Neurology Tags: Funct Neurol Source Type: research