Mitochondrial complex IV mutation increases reactive oxygen species production and reduces lifespan in aged mice

ConclusionOur findings demonstrate that a complex IV mutation leads to mitochondrial dysfunction that translates into survival.

Source: Acta Physiologica - November 20, 2018 Category: Physiology Authors: Gesine Reichart, Johannes Mayer, Cindy Zehm, Timo Kirschstein, Tursonjan Tokay, Falko Lange, Simone Baltrusch, Markus Tiedge, Georg Fuellen, Saleh Ibrahim, R üdiger Köhling Tags: ORIGINAL ARTICLE Source Type: research