Advances of supercritical fluid chromatography in lipid profiling

Publication date: Available online 17 November 2018Source: Journal of Pharmaceutical AnalysisAuthor(s): Yang Yang, Yanshan Liang, Jina Yang, Fengying Ye, Ting Zhou, Li GongkeAbstractSupercritical fluid chromatography (SFC) meets with great favor due to its high efficiency, low organic solvent consumption, and the specialty for the identification of the isomeric species. This review describes the advances of SFC in targeted and untargeted lipid profiling. The advancement of the SFC instruments and the stationary phases were summarized. Typical applications of SFC to the targeted and untargeted lipid profiling were discussed in detail. Moreover, the perspectives of SFC in the lipid profiling were also proposed. As a useful and promising tool for investigating lipids in vitro and in vivo, SFC will predictably obtain further development.
Source: Journal of Pharmaceutical Analysis - Category: Drugs & Pharmacology Source Type: research