Evaluation of DNA damage in spinal cord and mutagenic effect of a Ph α1β recombinant toxin with analgesic properties from the Phoneutria nigriventer spider

In conclusion, the recombinant form has cytotoxic, genotoxic and mutagenic effects, ev idenced in doses five time above the therapeutic dose.This article is protected by copyright. All rights reserved.

Source: Basic and Clinical Pharmacology and Toxicology - November 17, 2018 Category: Drugs & Pharmacology Authors: Alessandra Hubner de Souza, Luiza Gabriela da Rosa, Michel Rossi Uliano, Lismare da Silva Prado, Alice Gomes Ferraz, Lucas Umpierre Conter, Ivana Grivicich, Eliane Dallegrave, Marcus Vin ícius Gomez, Jaqueline Nascimento Picada Tags: Original Article Source Type: research