Phase 1 lead ‐in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma

ConclusionsMemantine, mefloquine, and metformin can be combined safely with TMZ in patients with newly diagnosed glioblastoma.

Source: Cancer - October 25, 2018 Category: Cancer & Oncology Authors: Stefania Maraka, Morris D. Groves, Aaron G. Mammoser, Isaac Melguizo ‐Gavilanes, Charles A. Conrad, Ivo W. Tremont‐Lukats, Monica E. Loghin, Barbara J. O’Brien, Vinay K. Puduvalli, Erik P. Sulman, Kenneth R. Hess, Kenneth D. Aldape, Mark Tags: Original Article Source Type: research