Lipoprotein(a) and Low ‐density lipoprotein apolipoprotein‐B metabolism following apheresis in patients with elevated lipoprotein(a) and coronary artery disease

ConclusionsIn patients with elevated Lp(a), the fractional catabolism of Lp(a) is slower than that of LDL ‐apoB particles, implying that different metabolic pathways are involved in the catabolism of these lipoproteins. These findings have implications for new therapies for lowering apolipoprotein(a) and apoB to prevent atherosclerotic cardiovascular disease.This article is protected by copyright. All rights reserved.

Source: European Journal of Clinical Investigation - November 17, 2018 Category: General Medicine Authors: Louis Ma, Elisa Waldmann, Esther M. M. Ooi, Dick C. Chan, Hugh P. R. Barrett, Gerald F. Watts, Klaus G. Parhofer Tags: Original Paper Source Type: research