The impact of UGT1A1 genetic polymorphism on toxicity in unresectable pancreatic cancer patients undergoing FOLFIRINOX

In conclusion, patients with heterozygous UGT1A1 polymorphisms treated with the original FOLFIRINOX regimen experienced severe toxicity more frequently than patients with wild type UGT1A1.This article is protected by copyright. All rights reserved.

Source: Cancer Science - November 17, 2018 Category: Cancer & Oncology Authors: Hiromichi Shirasu, Akiko Todaka, Katsuhiro Omae, Hirofumi Fujii, Nobumasa Mizuno, Masato Ozaka, Hideki Ueno, Satoshi Kobayashi, Kazuhiro Uesugi, Noritoshi Kobayashi, Hideyuki Hayashi, Kentaro Sudo, Naohiro Okano, Yosuke Horita, Keiko Kamei, Tags: Original Article Source Type: research