Activation of Toll ‐like receptor 7 signaling in labial salivary glands of primary Sjögren's syndrome patients

ConclusionOur findings suggest that TLR7 is dominantly expressed in both MNCs and ducts with downstream signals for type I IFNs, indicating that TLR7 ‐dominant innate immunity is related to the development of sialadenitis in pSS.This article is protected by copyright. All rights reserved.

Source: Clinical and Experimental Immunology - November 17, 2018 Category: Allergy & Immunology Authors: Toshimasa Shimizu, Hideki Nakamura, Ayuko Takatani, Masataka Umeda, Yoshiro Horai, Shota Kurushima, Toru Michitsuji, Yoshikazu Nakashima, Atsushi Kawakami Tags: Original Article Source Type: research