Prostaglandin E2 decrease in induced sputum of hypersensitive asthmatics during oral challenge with aspirin

ConclusionsAspirin ‐precipitated bronchoconstriction is associated with a decrease in airway PGE2 biosynthesis. These results support the mechanism of PGE2 biosynthesis inhibition as a trigger for bronchoconstriction in NERD.This article is protected by copyright. All rights reserved.

Source: Allergy - November 17, 2018 Category: Allergy & Immunology Authors: Lucyna Mastalerz, Katarzyna Ewa Tyrak, Maria Ignacak, Ewa Konduracka, Filip Mejza, Adam Ćmiel, Michał Buczek, Adrianna Kot, Krzysztof Oleś, Marek Sanak Tags: Original Article: Experimental Allergy and Immunology Source Type: research