Ex Vivo Culture of Cells Derived From Circulating Tumour Cell Xenograft to support Small Cell Lung Cancer Research and Experimental Therapeutics

Conclusion and ImplicationsShort term cultures of CDX provide a tractable platform to screen new treatments, identify predictive and pharmacodynamic biomarkers and interrogate mechanisms of resistance to better understand progression of this recalcitrant tumour.

Source: British Journal of Pharmacology - November 14, 2018 Category: Drugs & Pharmacology Authors: Alice Lallo, Sakshi Gulati, Maximilian W Schenk, Garima Khandelwal, Ulrika Warpman Berglund, Ioannis S Pateras, Christopher P E Chester, Therese M Pham, Christina Kalderen, Kristopher K Frese, Vassilis G Gorgoulis, Crispin Miller, Fiona Blackh Tags: RESEARCH PAPER Source Type: research