Macrophage functions in wound healing

AbstractMacrophages play a crucial role in regeneration and consecutive phases of wound healing. In this review we summarize current knowledge on the ontogeny, origin, phenotypical heterogeneity and functional exchangeability of macrophages participating in these processes. We also describe the genetic, pharmacologic and bioengineering methods for manipulation of macrophage phenotype and functions and their potential for development of the novel, clinically applicable, therapies.

Source: Journal of Tissue Engineering and Regenerative Medicine - November 16, 2018 Category: Biotechnology Authors: Malgorzata Kloc, Rafik M. Ghobrial, Jarek Wosik, Aneta Lewicka, S ławomir Lewicki, Jacek Z. Kubiak Tags: REVIEW Source Type: research