Unilesional mycosis fungoides is associated with increased expression of microRNA ‐17~92, and Th1 skewing

ConclusionsUnilesional MF exhibits a microRNA profile distinct from conventional early MF, with a higher level of miR ‐17~92 members along with a Th1 skewing. These findings suggest a robust reactive T‐cell immune response in unilesional MF and might account for the localized nature of this disease.This article is protected by copyright. All rights reserved.

Source: British Journal of Dermatology - November 15, 2018 Category: Dermatology Authors: L. Moyal, B. Gorovitz ‐Haris, S. Yehezkel, J. Jacob‐Hirsch, V. Bershtein, A. Barzilai, C. Rotem, S. Sherman, I. Amitay‐Laish, M. Feinmesser, E. Hodak Tags: Original Article Source Type: research