Th2 cell differentiation from naive CD4+ T cells is enhanced by autocrine CC chemokines in atopic diseases

Conclusions& Clinical RelevanceThese data suggest that CCL17 and CCL22 produced by TSLP ‐primed naïve CD4+ T cells in asthma might contribute to an increase in Th2 cells via autocrine loops.This article is protected by copyright. All rights reserved.

Source: Clinical and Experimental Allergy - November 15, 2018 Category: Allergy & Immunology Authors: Hirokuni Hirata, Tatsuo Yukawa, Ayae Tanaka, Tomoyuki Miyao, Takeshi Fukuda, Yasutsugu Fukushima, Kazuhiro Kurasawa, Masafumi Arima Tags: Original Article ‐Basic Mechanisms in Allergic Disease Source Type: research