Efficacy of an artificial pancreas device for achieving tight perioperative glycemic control in living donor liver transplantation

In this study, we aimed to control the perioperative glucose levels consecutively for 24  hours from the induction of anesthesia. The average blood glucose level in the artificial pancreas group was significantly lower than that in the sliding scale group (118 vs. 141 mg/dL,P  <  0.05). The postoperative bacterial infection rate of the artificial pancreas group was significantly lower than that of the sliding scale group within one month after LDLT (35.7% vs. 78.6%,P  <  0.05). Multiple regression analysis showed non‐application of artificial endocrine pancreas as a significant risk factor of posttransplant infection. The artificial endocrine pancreas enabled the perioperative glucose level to be stably controlled without hypoglycemia. Artificial pancreas may re duce the incidence of postoperative infection after LDLT.

Source: Artificial Organs - November 15, 2018 Category: Transplant Surgery Authors: Akihiko Soyama, Tota Kugiyama, Takanobu Hara, Masaaki Hidaka, Takashi Hamada, Satomi Okada, Tomohiko Adachi, Shinichiro Ono, Mitsuhisa Takatsuki, Susumu Eguchi Tags: MAIN TEXT ARTICLE Source Type: research