Three ‐Dimensional Numerical Simulations of Aspiration Process: Evaluation of Two Penumbra Aspiration Catheters Performance

AbstractAcute ischemic stroke (AIS) is the leading cause of mortality and disability worldwide. AIS occur while cerebral arteries become blocked by embolism or thrombosis. Aspiration thrombectomy is a promising interventional device to extract massive clots from occluded cerebral arteries. The aim of this article is to develop a computer ‐aided method to clarify the performance of aspiration catheter and identify the risks of aspiration for each specific AIS patient. In order to simulate the aspiration process, a three‐dimensional fluid‐structure interaction (FSI) method was developed. The blood clot was modeled as a porous me dia which composed of viscoelastic fibrin networks. The finite element method (FEM) was implemented to compute the blood flow dynamics in the simplified cerebral vessel. The introduced clot model was validated by comparing the numerical results with experimental data. Furthermore, the analytical sol ution of the flow through the partially porous pipe was considered to validate FEM. In this research, the performance of two model of the Penumbra aspiration catheter—4MAX and 5MAX—were were compared at three distinct suction pressures. The aspiration ratio of the clot, aspiration time, amount o f free fragments, wall shear stress (WSS), and extracted volume of the blood were calculated to evaluate catheters performance. At suction pressure −50 kPa, the aspiration ratio of 5MAX catheter reached 86.58% within 1.36 s. However, in 4MAX case, aspir...
Source: Artificial Organs - Category: Transplant Surgery Authors: Tags: Main Text Article Source Type: research