Propeptide glycosylation and galectin ‐3 binding decrease proteolytic activation of human proMMP‐9/progelatinase B

In conclusion, modification of MMP‐9 propeptide glycosylation is a fine‐tuning mechanism and co‐determines the specific activity of MMP‐9 in physiology and p athology.This article is protected by copyright. All rights reserved.

Source: FEBS Journal - November 13, 2018 Category: Research Authors: Lise Boon, Estefania Ugarte ‐Berzal, Erik Martens, Jennifer Vandooren, Vasily Rybakin, Didier Colau, Monica Gordon‐Alonso, Pierre van der Bruggen, Walter Stöcker, Christoph Becker‐Pauly, Peter Witters, Eva Morava‐Kozics, Jaak Jaeken, Tags: Original Article Source Type: research