Safety and efficacy of colistin alone or in combination in adults with Acinetobacter baumannii infection: a systematic review and meta-analysis

Acinetobacter baumannii is an important Gram negative opportunistic nosocomial bacterial, which is listed as one of the six most important multidrug resistant (MDR) pathogens in hospitals worldwide by the Infectious Diseases Society of America in 2006 [1,2]. 2017, A. baumannii is also classified in the highest level of “critical” by WHO because it is resistant to a great deal of antibiotics, including carbapenems [3]. A. baumannii can cause a broad range of severe infections, including ventilator associated pneumonia (VAP), bloodstream infections, skin and soft tissue infections, urinary tract infections, woun d infections and secondary meningitis et al.
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Tags: Review Source Type: research