Association between inflammatory bowel disease and uveal melanoma: case report of two young adults and a literature review

DiscussionChronic inflammation can promote cell proliferation and growth. The use of immunomodulatory drugs is associated with an increased risk of developing melanoma and non-melanoma skin cancer. The two patients described in this report both had long-standing IBD treated with immunomodulatory drugs. It seems reasonable to suggest that these two factors may have promoted the development of uveal melanoma. More studies are warranted to investigate and confirm this possible association.
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research