Identifying the optimal regional predictor of right ventricular global function: a high ‐resolution three‐dimensional cardiac magnetic resonance study

SummaryRight ventricular (RV) function has prognostic value in acute, chronic and peri ‐operative disease, although the complex RV contractile pattern makes rapid assessment difficult. Several two‐dimensional (2D) regional measures estimate RV function, however the optimal measure is not known. High‐resolution three‐dimensional (3D) cardiac magnetic resonance cine imaging was acquired in 300 healthy volunteers and a computational model of RV motion created. Points where regional function was significantly associated with global function were identified and a 2D, optimised single‐point marker (SPM‐O) of global function developed. This marker was prospectively compared with tricuspid annular plane systolic excursion (TAPSE), septum‐freewall displacement (SFD) and their fractional change (TAPSE‐F, SFD‐F) in a test cohort of 300 patients in the prediction of RV ejection fraction. RV ejection fraction was significantly associated with systolic function in a co ntiguous 7.3 cm2 patch of the basal RV freewall combining transverse (38%), longitudinal (35%) and circumferential (27%) contraction and coinciding with the four ‐chamber view. In the test cohort, all single‐point surrogates correlated with RV ejection fraction (p< 0.010), but correlation (R) was higher for SPM ‐O (R = 0.44, p< 0.001) than TAPSE (R = 0.24, p< 0.001) and SFD (R = 0.22, p< 0.001), and non ‐significantly higher than TAPSE‐F (R = 0.40, p< 0.001) and SFD ‐F (R = 0.43, ...
Source: Anaesthesia - Category: Anesthesiology Authors: Tags: Original Article Source Type: research