Identification of functionally primitive and immunophenotypically distinct subpopulations in secondary acute myeloid leukemia by mass cytometry

ConclusionsThe identification of this cellular subpopulation highlights the limitations of manual gating in sAML. Our study demonstrates the potential for mass cytometry to elucidate rare subpopulations in highly heterogeneous tumors by utilizing unsupervised high dimensional analysis. © 2018 International Clinical Cytometry Society

Source: Cytometry Part B: Clinical Cytometry - November 13, 2018 Category: Molecular Biology Authors: Shovik Bandyopadhyay, Jared S. Fowles, Liyang Yu, Daniel A.C. Fisher, Stephen T. Oh Tags: Original Article Source Type: research