On ‐Tissue Hydrogel‐Mediated Nondestructive Proteomic Characterization: Application to fr/fr and FFPE Tissues and Insights for Quantitative Proteomics Using a Case of Cardiac Myxoma

ConclusionThe methodology successfully detects numerous protein signals from FFPE and frozen specimens and is able to differentiate between tissue regions. A fast and reliable tissue preparation for quantitative protein analysis by minimum sample manipulation is developed. This offers an option for on ‐tissue proteomics analysis while preserving the inherent spatial information on the tissue.

Source: Proteomics. Clinical Applications - November 12, 2018 Category: Biochemistry Authors: Domenico Taverna, Chiara Mignogna, Gianluca Santise, Marco Gaspari, Giovanni Cuda Tags: Technical Brief Source Type: research