Stochastic analysis of a heterogeneous micro-finite element model of a mouse tibia

Micro computed tomography ( μCT) imaging has become an important tool to reveal the detailed internal structure of bone, both ex vivo and in vivo [1,2]. μCT images can be used to generate micro-finite element (μFE) models, in which the element size is on the order of micrometers, to investigate the mechanical behavior of bo ne, the mechanism of bone mechano-regulation, and the strength of bone after medical intervention [3–8]. Because the homogeneous μFE models lack realistic spatial variations in bone properties and exhibit limited accuracy, heterogeneous μFE models with heterogeneous material properties have been adopted widely in previous studies [9–11].
Source: Medical Engineering and Physics - Category: Biomedical Engineering Authors: Tags: Technical note Source Type: research