Promise of Combining Antifungal Agents in Denture Adhesives to Fight Candida Species Infections

ConclusionsAntimicrobial peptides and antimicrobial lipids had diminished activities in 1% adhesive, suggesting that components in adhesives may inactivate local innate immune factors in the oral cavity, possibly predisposing denture wearers toCandida species infections. More importantly, antifungal agents retained their anti ‐C. albicans activities in denture adhesive, strongly suggesting that antifungal agents could be candidates for inclusion in adhesive formulations and used as prescribed topical treatments for individuals with denture stomatitis.

https://onlinelibrary.wiley.com:443/doi/abs/10.1111/jopr.12565?af=R

Source: Journal of Prosthodontics - October 8, 2018 Category: Dentistry Authors: Jorge L. Garaicoa, Carol L. Fischer, Amber M. Bates, Julie Holloway, Gustavo Avila ‐Ortiz, Janet M. Guthmiller, Georgia K. Johnson, Clark Stanford, Kim A. Brogden Tags: Original Manuscript Source Type: research