Ectopic nerve growth factor prevents proliferation in glioma cells by senescence induction

ConclusionsThese findings provide the first evidence that NGF can induce senescence of PLGG cells in a receptor ‐mediated fashion, thus supporting the hypothesis that in the clinical setting NGF might be beneficial to pediatric glioma patients.

Source: Journal of Cellular Physiology - November 11, 2018 Category: Cytology Authors: Daniela Meco, Angela Maria Di Francesco, Linda Melotti, Antonio Ruggiero, Riccardo Riccardi Tags: ORIGINAL RESEARCH ARTICLE Source Type: research